ABO Ophthalmology Complete Practice Exam 2025

Chronic steroid use is associated with several ocular complications, one of which is the development of cataracts. This occurs because steroids can induce lens opacification, particularly posterior subcapsular cataracts, which affect vision clearer in the intermediate and near vision first. The exact mechanism involves steroid-induced alterations in lens metabolism and the promotion of protein aggregation in the lens, leading to cloudiness.

While other complications can arise from steroid use, such as an increase in intraocular pressure or the potential for ocular hypertension, the formation of cataracts is a well-documented and primary concern that is especially pertinent given the frequency with which corticosteroids are prescribed for various ocular conditions. Understanding the risks of cataract formation is crucial for monitoring patients on long-term steroid therapy and advising them on potential visual impairments that may arise as a result.